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MYP_146551
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Basic Information
EF peptide
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Flavivirus ▸ Anti-Dengue virus
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Phosphodiesterase inhibition ▸ CaMPDE inhibitor
Enzyme modulation ▸ Enzyme inhibition ▸ Renin inhibition ▸ Renin inhibitory
Metabolic ▸ Lipid metabolism ▸ Lipid-lowering activity
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
2 amino acids
C14H18N2O5
Standard
Sequence
EF
Physicochemical Analysis
294.30 Da
4.05
-1.16
-1.33
-0.5816
-0.35
0.75
0.23
5.00
0.00
0.5000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
129.72
-0.01
4.0
4.0
8.0
21.0
1.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0011174 VERIFIED: NO
Provenance & Taxonomy
Allium cepa [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Lipogenesis Attenuator Enzyme inhibitory
Angiotensin-I converting enzyme
RECORD: Rec_0021390 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
dengue virus 2(DENV2):inhibition of viral entry in Vero cells
96.5 μM
IC50
PaperPubMed PMID: 24612829 PMID24612829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24612829/
RECORD: Rec_0026759 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Replication inhibition
Inhibition of viral replication in Vero cells
200 μM
% inhibition
Mammalian: 1 h; Yeast: 30 min; E. coli: >10 h
PaperPeptide inhibitors against dengue virus infection. | Panya A, Bangphoomi K, Choowongkomon K, Yenchitsomanus PT. | Chem Biol Drug Des. 2014 Aug;84(2):148-57. | DOI:10.1111/cbdd.12309 | PMID:24612829 PMID24612829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24612829/
RECORD: Rec_0043041 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-DENV Entry inhibition
Dengue virus 2(DENV2) | Vero cells
96.5 μM
IC50
Mammalian: 1 h; Yeast: 30 min; E. coli: >10 h
PaperPeptide inhibitors against dengue virus infection. | Panya A, Bangphoomi K, Choowongkomon K, Yenchitsomanus PT. | Chem Biol Drug Des. 2014 Aug;84(2):148-57. | DOI:10.1111/cbdd.12309 | PMID:24612829 PMID24612829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24612829/
RECORD: Rec_0063821 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Vero cells
0 % Cytotoxicity
Cytotoxicity
PMID24612829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24612829/
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