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MYP_146520
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Basic Information
Lunasin
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
43 amino acids
C204H321N65O78S3
Standard
Sequence
SKWQHQQDSCRKQLQGVNLTPCEKHIMEKIQGRGDDDDDDDDD
Physicochemical Analysis
5028.31 Da
4.50
-6.37
-6.72
-0.1481
-1.76
0.50
-0.44
48.38
43.02
0.0233
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2387.68
-30.38
80.0
77.0
177.0
350.0
5.0
49.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0080625 VERIFIED: YES
Provenance & Taxonomy
Glycine max [Plant]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID10331812 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10331812/
RECORD: Rec_0088547 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0143902 VERIFIED: YES
Provenance & Taxonomy
Glycine max [Plant]; Fabaceae [Plant]
Lunasin
3847; 3803
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID23419988 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23419988/
RECORD: Rec_0167864 VERIFIED: YES
Provenance & Taxonomy
Glycine max [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Antioxidant Anti-inflammatory
PaperA soybean cDNA encoding a chromatin-binding peptide inhibits mitosis of mammalian cells.
RECORD: Rec_0207390 VERIFIED: YES
Provenance & Taxonomy
Glycine max [Plant]
3847.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory
PaperFern¨¢ndez-Tom¨¦ S., Indiano-Romacho P., Mora-Guti¨¦rrez I., P¨¦rez-Rodr¨ªguez L., Ortega Moreno L., Marin A. C., Bald¨¢n-Mart¨ªn M., Moreno-Monteagudo J. A.. Lunasin peptide is a modulator of the immune response in the human gastrointestinal tract. Mol. Nutr. Food Res., 65, 2001034, 2021.
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