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MYP_146517
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Basic Information
Temporin-1DRa [Aib6]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
HFLGTXVNLAKKIL
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0133519 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6
Bio-Activity Profile
Hemolytic
human red blood cells
>300 μM
HC50
PMID17767978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17767978/
RECORD: Rec_0258225 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6
Bio-Activity Profile
Antimicrobial Antibacterial
Candida albicans ATCC 900280
64 μM
MIC
PMID17767978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17767978/
RECORD: Rec_0271811 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25726
128 μM
MIC
PMID17767978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17767978/
RECORD: Rec_0275728 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6
Bio-Activity Profile
Anticancer Cytotoxic
Human hepatocellular carcinoma HepG2
200 μM
LC50
PMID17767978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17767978/
RECORD: Rec_0320029 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=AIB (Aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Anticancer
HepG2
200 μM
LC50
PaperPubMed PMID: 17767978 PMID17767978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17767978/
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