Peptide Database

Peptide NameMolt-inhibiting hormone

Function Ontology

Developmental biology ▸ Molting regulation

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC370H585N97O110S6

DescriptionStandard

        QVFDQACKGIYDRAIFKKLELVCDDCYNLYRKPKVATTCRENCYANSVFRQCLDDLLLINVVDEYISGVQIV
    

Molecular Weight8344.58 Da

Isoelectric Point (pI)5.17

Net Charge (pH 7.0)-1.29

Net Charge (pH 7.4) -1.61

Charge Density (pH 7.0) -0.0180

GRAVY Index0.01

Hydrophobic Moment 0.62

Boman Index0.00

Instability Index15.27

Aliphatic Index 102.78

Aromaticity 0.1111

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3398.12

LogP -28.56

H-bond Donors 122.0

H-bond Acceptors 115.0

Rotatable Bonds 279.0

Heavy Atoms 583.0

Ring Count 9.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0072120 VERIFIED: YES

Provenance & Taxonomy

OrganismProcambarus bouvieri [Animal]

FamilyMolt-inhibiting hormone

Tax ID6729

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

C-TermAmidation

Disulfide7-43; 23-39; 26-52

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Molting regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0238243 VERIFIED: YES

Provenance & Taxonomy

OrganismProcambarus bouvieri [Animal]

FamilyArthropod CHH/MIH/GIH/VIH hormone

Tax ID6729

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Arthropod neurohormone

RECORD: Rec_0291996 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/