Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length194 amino acids

Chemical FormulaC966H1538N266O262S7

DescriptionStandard

        PTLPPMAHEPSLLLAVTEFVASSAAFTYFTAGALRRNISSDMLPRRFPLQLRTKSMEVFSPQLQELYPDQPMELHLWARQQPLLSCHPDALHGTLLGSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGAVRLTGLVPDPELGLSSPRTWAQGLPVPQVKRLETLLKFGLWLFGVPRANSKCCPRAVP
    

Molecular Weight21294.63 Da

Isoelectric Point (pI)9.73

Net Charge (pH 7.0)6.30

Net Charge (pH 7.4) 5.97

Charge Density (pH 7.0) 0.0325

GRAVY Index0.03

Hydrophobic Moment 0.57

Boman Index0.09

Instability Index57.45

Aliphatic Index 97.06

Aromaticity 0.0722

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8274.20

LogP -100.87

H-bond Donors 285.0

H-bond Acceptors 279.0

Rotatable Bonds 669.0

Heavy Atoms 1501.0

Ring Count 43.0

Amide Bonds 207.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0058736 VERIFIED: NO

Provenance & Taxonomy

OrganismNesospiza acunhae [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria