Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length472 amino acids

Chemical FormulaC2353H3707N597O683S20

DescriptionStandard

        MLPSVVVLLMFISGTCAENPAIQFVLTNKGLQKGKHRVTDWIQQHLENVTLPDISSDIHIPILGNIHYTLTDISITKCDLPEPSVEFYPNVTGFKTSISGLSVALTGEWETHYHIIHDGGSLDMAVFDLNVISAVELGKDAGGHLSVSSISCDAQVGDVDVRFHGGDSWIFQPFVKYFKRQIIGKIQKSICPSVEEMIVTLESHLQAMNVSFDVNQLLSLDLNLTSVPVVDATSLNLGLKGEFYNIRTHSEPPFKPKSFTLPEQQGYMMSVGLSEFTLNSASYGYYSAGLLQVDINDSMIPPYCPVHLNTTSMGRYIPQLPKLFPGLPMSLKVYARQVPVFFFQSDVVKLGLQGSVKAFAIQRNGTQTPLLTLDVDSGFSGKMWIIDGRLKGMVKMDNVTLKLVASEVGSFSTDTMEKDLRLGLPVVLAKTVNKVLAQGLVLPRFKQAQLVNSVLKVKEGFMAVSSDVEVYF
    

Molecular Weight51928.49 Da

Isoelectric Point (pI)5.95

Net Charge (pH 7.0)-6.46

Net Charge (pH 7.4) -7.47

Charge Density (pH 7.0) -0.0137

GRAVY Index0.14

Hydrophobic Moment 0.80

Boman Index0.16

Instability Index38.81

Aliphatic Index 101.06

Aromaticity 0.0869

Extinction Coeff. Reduced 41370.00

Extinction Coeff. Oxidized 41620.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0320282 VERIFIED: NO

Provenance & Taxonomy

OrganismAnabas testudineus [Bacterium]

FamilyBPI

Tax ID64144

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence