Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC342H534N96O89S8

DescriptionStandard

        MKLHLVFFILLFWVTISPPKRRDPEYGSVNLSKECRRSSGQCRAQCYDNEMRVAFCLKPGIHYCM
    

Molecular Weight7671.01 Da

Isoelectric Point (pI)9.19

Net Charge (pH 7.0)4.63

Net Charge (pH 7.4) 4.22

Charge Density (pH 7.0) 0.0712

GRAVY Index-0.18

Hydrophobic Moment 0.50

Boman Index-0.04

Instability Index72.13

Aliphatic Index 74.92

Aromaticity 0.1231

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2980.12

LogP -23.93

H-bond Donors 110.0

H-bond Acceptors 104.0

Rotatable Bonds 250.0

Heavy Atoms 535.0

Ring Count 15.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0040917 VERIFIED: NO

Provenance & Taxonomy

OrganismHeterocephalus glaber [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence