Peptide Database

Peptide NamePyosin cloacin_T_dom domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length177 amino acids

Chemical FormulaC851H1285N229O260S8

DescriptionStandard

        MTRIMSTMLYIHPPHGCCAFKMEINMSDNETVPTQGVDYGHTIVGWPVRPKWGQPDAGASIGINPDFDPVTGNGWLPEEDGYHHDLPAGTPADVQSAINQVKQAGGLMSVDLRKLRPAAGYPWDQTVAWDPVFVYFPAKAVSDSDLSAGSLPETVPVHSRIQDDVHDGAQFISVTGS
    

Molecular Weight19140.20 Da

Isoelectric Point (pI)4.75

Net Charge (pH 7.0)-10.89

Net Charge (pH 7.4) -11.52

Charge Density (pH 7.0) -0.0615

GRAVY Index-0.29

Hydrophobic Moment 0.63

Boman Index0.10

Instability Index42.75

Aliphatic Index 71.58

Aromaticity 0.0847

Extinction Coeff. Reduced 34950.00

Extinction Coeff. Oxidized 35075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7644.48

LogP -79.18

H-bond Donors 256.0

H-bond Acceptors 264.0

Rotatable Bonds 593.0

Heavy Atoms 1348.0

Ring Count 44.0

Amide Bonds 189.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0070270 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli