Peptide Database

Peptide NameBeta-defensin 25 (BD-25) (mBD-25) (Defensin; beta 25)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC354H556N98O95S8

DescriptionStandard

        MAKWILLIVALLVLSHVPPGSTEFKRCWNGQGACRTFCTRQETFMHLCPDASLCCLSYSFKPSRPSRVGDV
    

Molecular Weight7961.32 Da

Isoelectric Point (pI)8.91

Net Charge (pH 7.0)3.62

Net Charge (pH 7.4) 3.20

Charge Density (pH 7.0) 0.0510

GRAVY Index0.16

Hydrophobic Moment 0.51

Boman Index0.09

Instability Index66.79

Aliphatic Index 80.99

Aromaticity 0.0986

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3054.10

LogP -28.15

H-bond Donors 114.0

H-bond Acceptors 109.0

Rotatable Bonds 252.0

Heavy Atoms 555.0

Ring Count 16.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0371096 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic