Peptide Database

Peptide NameAmolopin-1a antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC365H591N93O106S6

DescriptionStandard

        MFTLKKSLLLLFFLGTINLSLCEQERNADEEERRDDDEMDVEVEKRFLPMLAGLAANFLPKLFCKITKKC
    

Molecular Weight8170.55 Da

Isoelectric Point (pI)5.07

Net Charge (pH 7.0)-2.51

Net Charge (pH 7.4) -2.80

Charge Density (pH 7.0) -0.0358

GRAVY Index-0.12

Hydrophobic Moment 0.68

Boman Index-0.03

Instability Index35.49

Aliphatic Index 97.57

Aromaticity 0.0857

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3241.79

LogP -23.02

H-bond Donors 113.0

H-bond Acceptors 110.0

Rotatable Bonds 285.0

Heavy Atoms 570.0

Ring Count 8.0

Amide Bonds 73.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0330424 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops loloensis [Animal]

FamilyBrevinin

Tax ID318551

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Cytolytic Non-hemolytic Non-ribosomal