Peptide Database

Peptide NameCycloviolacin O15

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC120H197N35O36S6

DescriptionStandard

        LKCGESCFAGKCYTPGCTCSRPICKKN
    

Molecular Weight2898.45 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)3.70

Net Charge (pH 7.4) 3.40

Charge Density (pH 7.0) 0.1370

GRAVY Index-0.29

Hydrophobic Moment 0.51

Boman Index-0.10

Instability Index42.95

Aliphatic Index 32.59

Aromaticity 0.0741

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1149.86

LogP -14.94

H-bond Donors 46.0

H-bond Acceptors 46.0

Rotatable Bonds 94.0

Heavy Atoms 197.0

Ring Count 4.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0246186 VERIFIED: YES

Provenance & Taxonomy

OrganismClitoria ternatea [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)