Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC487H781N123O138S8

DescriptionStandard

        MKLLLVLFILLFEVPTDGAGLRKCFNNITGYCRKKCKIGEIYEVGCLSGKLCCVNEGESKKYLEKAHKPREPDGEVSDGKMDYNILPTITIFTVQF
    

Molecular Weight10823.67 Da

Isoelectric Point (pI)8.21

Net Charge (pH 7.0)1.54

Net Charge (pH 7.4) 1.15

Charge Density (pH 7.0) 0.0160

GRAVY Index-0.06

Hydrophobic Moment 0.56

Boman Index0.05

Instability Index27.06

Aliphatic Index 93.33

Aromaticity 0.0938

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4199.07

LogP -32.30

H-bond Donors 149.0

H-bond Acceptors 149.0

Rotatable Bonds 368.0

Heavy Atoms 756.0

Ring Count 14.0

Amide Bonds 100.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0039067 VERIFIED: NO

Provenance & Taxonomy

OrganismProlemur simus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence