Peptide Database

Peptide NamePore-forming peptide ameobapore C

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length101 amino acids

Chemical FormulaC487H818N118O140S9

DescriptionStandard

        MKLFVLLCVFVLCLASQEKQQDREIPVLCPVCTSLVGKLIDLVLGGAVDKVTDYLETLCAKADGLVETLCTKIVSYGIDKLIEKILEGGSAKLICGLIHAC
    

Molecular Weight10855.00 Da

Isoelectric Point (pI)5.26

Net Charge (pH 7.0)-2.48

Net Charge (pH 7.4) -2.89

Charge Density (pH 7.0) -0.0245

GRAVY Index0.77

Hydrophobic Moment 0.74

Boman Index0.26

Instability Index32.58

Aliphatic Index 137.92

Aromaticity 0.0396

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4079.90

LogP -27.85

H-bond Donors 147.0

H-bond Acceptors 148.0

Rotatable Bonds 371.0

Heavy Atoms 754.0

Ring Count 7.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0185831 VERIFIED: NO

Provenance & Taxonomy

OrganismEntamoeba histolytica [Protist]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Antiparasitic Cytolytic Non-hemolytic Non-ribosomal

MethodQualitative functional evidence