Peptide Database

Peptide NameBeta-defensin 119 (Beta-defensin 120) (Defensin; beta 119) (Defensin; beta 120)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC438H693N119O123S9

DescriptionStandard

        MKLLYLFLAILLAIEEPVISGKRHILRCMGNSGICRASCKKNEQPYLYCRNYQSCCLQSYMRISISGKEEDTDWSYEKQWPRLP
    

Molecular Weight9882.50 Da

Isoelectric Point (pI)8.80

Net Charge (pH 7.0)3.54

Net Charge (pH 7.4) 3.15

Charge Density (pH 7.0) 0.0421

GRAVY Index-0.34

Hydrophobic Moment 0.66

Boman Index-0.05

Instability Index83.17

Aliphatic Index 85.95

Aromaticity 0.1071

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20315.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3934.72

LogP -32.63

H-bond Donors 144.0

H-bond Acceptors 137.0

Rotatable Bonds 330.0

Heavy Atoms 689.0

Ring Count 16.0

Amide Bonds 90.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0131912 VERIFIED: NO

Provenance & Taxonomy

OrganismGorilla gorilla gorilla [Animal]

FamilyBeta-defensin; Defensin

Tax ID9595

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic