Peptide Database

Peptide NameLycosin-II

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC124H204N36O27

DescriptionStandard

        VWLSALKFIGKHLAKHQLSKLGR
    

Molecular Weight2631.17 Da

Isoelectric Point (pI)11.33

Net Charge (pH 7.0)4.90

Net Charge (pH 7.4) 4.59

Charge Density (pH 7.0) 0.2132

GRAVY Index0.03

Hydrophobic Moment 0.58

Boman Index0.06

Instability Index3.86

Aliphatic Index 123.04

Aromaticity 0.0870

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1026.20

LogP -5.77

H-bond Donors 37.0

H-bond Acceptors 34.0

Rotatable Bonds 91.0

Heavy Atoms 187.0

Ring Count 5.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0021352 VERIFIED: YES

Provenance & Taxonomy

OrganismLycosa singoriensis [Animal]

FamilyCationic peptide 04 (cupiennin); 05 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiofilm Anti-Gram-negative Anti-Gram-positive Anti-inflammatory Cytotoxic Hemolytic

TargetAcinetobacter baumannii

RECORD: Rec_0267141 VERIFIED: YES

Provenance & Taxonomy

OrganismLycosa singoriensis [Animal]

FamilyCationic peptide 04 (cupiennin); 05 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiofilm Anti-Gram-negative Anti-Gram-positive Anti-inflammatory Cytotoxic Hemolytic

TargetStaphylococcus epidermidis

RECORD: Rec_0312711 VERIFIED: YES

Provenance & Taxonomy

OrganismLycosa singoriensis [Animal]

FamilyCationic peptide 04 (cupiennin); 05 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiofilm Anti-Gram-negative Anti-Gram-positive Anti-inflammatory Cytotoxic Hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0397598 VERIFIED: YES

Provenance & Taxonomy

OrganismLycosa singoriensis [Animal]

FamilyCationic peptide 04 (cupiennin); 05 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiofilm Anti-Gram-negative Anti-Gram-positive Anti-inflammatory Cytotoxic Hemolytic

TargetPseudomonas aeruginosa

RECORD: Rec_0416101 VERIFIED: YES

Provenance & Taxonomy

OrganismLycosa singoriensis [Animal]

FamilyCationic peptide 04 (cupiennin); 05 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiofilm Anti-Gram-negative Anti-Gram-positive Anti-inflammatory Cytotoxic Hemolytic

TargetEscherichia coli