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MYP_146065
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Basic Information
Diketopiperazine (YC)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
2 amino acids
C12H16N2O4S
Standard
Sequence
YC
Physicochemical Analysis
284.33 Da
5.52
-0.25
-0.47
-0.1254
0.60
0.18
0.28
5.00
0.00
0.5000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
112.65
-0.24
5.0
5.0
6.0
19.0
1.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0205528 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HeLa (54.61 ± 0.02% Inhibition=10 μM ; 57.79 ± 0.02% Inhibition=100 μM)
PMID18436344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18436344/
RECORD: Rec_0296466 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: HT-29 (32.41 ± 0.03% Inhibition=10 μM; 52.27 ± 0.02% Inhibition=100 μM)
PMID18436344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18436344/
RECORD: Rec_0319722 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID18436344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18436344/
RECORD: Rec_0334456 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7 (35.15 ± 0.01% Inhibition=10 μM; 56.08 ± 0.01% Inhibition=100 μM)
PMID18436344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18436344/
RECORD: Rec_0335731 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID18436344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18436344/