Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC345H555N87O91S7

DescriptionStandard

        MKAFLLTLAALVLLSQVTLGSAEKCWNLRGSCREKCIKNEKLYIFCTSGKLCCLKPKFQPTYSLWPD
    

Molecular Weight7602.08 Da

Isoelectric Point (pI)9.19

Net Charge (pH 7.0)5.44

Net Charge (pH 7.4) 5.12

Charge Density (pH 7.0) 0.0812

GRAVY Index0.15

Hydrophobic Moment 0.34

Boman Index0.08

Instability Index27.74

Aliphatic Index 96.12

Aromaticity 0.1045

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2865.18

LogP -21.36

H-bond Donors 106.0

H-bond Acceptors 104.0

Rotatable Bonds 253.0

Heavy Atoms 530.0

Ring Count 12.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0252703 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris (Dog) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin