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MYP_146035
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
29 amino acids
C139H236N44O41S2
Standard
Sequence
SGTPEKERESGRLLGVVKRYIVCVRNPCP
Physicochemical Analysis
3243.76 Da
9.38
2.45
2.20
0.0843
-0.53
0.68
-0.21
28.79
80.34
0.0345
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1387.30
-14.90
51.0
46.0
106.0
226.0
4.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006254 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0023509 VERIFIED: YES
Provenance & Taxonomy
Heterometrus spinifer [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacterial and Candida test panel (see assay-specific records)
Broth microdilution MIC panel; assay-specific values stored in sibling records
PMID23000095 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23000095/
RECORD: Rec_0044260 VERIFIED: NO
Provenance & Taxonomy
Heterometrus spinifer [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli TOP10
3.75 OD_ID (dimensionless)
Me^x pooled intracellular expression growth assay; 4.5 h; rank 2606; Wald adj. p=0.2831
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0048195 VERIFIED: NO
Provenance & Taxonomy
Heterometrus spinifer [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Hemolytic
C. tropicalis, Also possesses
RECORD: Rec_0050737 VERIFIED: YES
Provenance & Taxonomy
Heterometrus spinifer [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida tropicalis AY 91009
48.6 μM
MIC
PMID23000095 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23000095/
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