Peptide Database

Peptide NameCathelicidin 6

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length158 amino acids

Chemical FormulaC805H1302N220O230S5

DescriptionStandard

        METQRASLSLGRWSLWLLLLGLALPSASAQALSYREAVLRAVDQFNEWSSEANLYRLLELDPPLKEDDENPNIPKPVSFRVKETVCPRTSQQPAEQCDFKENGLVKQCVGTVTLDAVKGKINITCEELQSVGRFKRFRKKFKKLFKKLSPVIPLLQLG
    

Molecular Weight17902.61 Da

Isoelectric Point (pI)9.25

Net Charge (pH 7.0)5.49

Net Charge (pH 7.4) 5.16

Charge Density (pH 7.0) 0.0347

GRAVY Index-0.30

Hydrophobic Moment 0.82

Boman Index-0.06

Instability Index37.13

Aliphatic Index 95.63

Aromaticity 0.0759

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7297.12

LogP -66.67

H-bond Donors 253.0

H-bond Acceptors 241.0

Rotatable Bonds 604.0

Heavy Atoms 1260.0

Ring Count 25.0

Amide Bonds 172.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0273363 VERIFIED: NO

Provenance & Taxonomy

OrganismBos mutus grunniens [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence