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MYP_145942
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Basic Information
L-K6 [L12W]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C80H144N20O15
Standard
Sequence
IKKILSKIKKLWK
Physicochemical Analysis
1626.12 Da
10.70
5.75
5.54
0.4426
-0.31
0.80
-0.16
9.61
150.00
0.0769
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
604.66
-0.06
22.0
21.0
62.0
115.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0039891 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus AS1.72
12.5 μM
MIC
PMID31824473;32023094;23710779 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31824473/
RECORD: Rec_0053524 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes; Human erythrocytes; HEK293T cells
>500; <1; 17 μM; %; %
HC50; Hemolysis at 3.125 μM; Cell killing assay at 3.125 μM
PMID31824473;32023094;23710779 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31824473/
RECORD: Rec_0074704 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecium
10.0 μM
MIC
PaperInvestigation of the role of tryptophan residues in cationic antimicrobial peptides to determine the mechanism of antimicrobial action.
RECORD: Rec_0081154 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli AS1.349
9.37 μM
MIC
PMID31824473;32023094;23710779 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31824473/
RECORD: Rec_0090945 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterobacter cloacae CGMCC 1.58
100 μM
MIC
PMID31824473;32023094;23710779 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31824473/
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