‹ ›
MYP_145942
← PREVIOUS NEXT → BACK
Basic Information
L-K6 [L12W]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C80H144N20O15
Standard
Sequence
IKKILSKIKKLWK
Physicochemical Analysis
1626.12 Da
10.70
5.75
5.54
0.4426
-0.31
0.80
-0.16
9.61
150.00
0.0769
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
604.66
-0.06
22.0
21.0
62.0
115.0
2.0
12.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0039891 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus AS1.72
12.5 μM
MIC
PMID31824473;32023094;23710779 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31824473/
RECORD: Rec_0053524 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (50% Hemolysis at >500 microM, Human erythrocytes (<1% Hemolysis at 3.125 microM, Human embryonic kidney HEK293T cells (17% Killing at 3.125 microM
500 μM
Hemolysis
PMID31824473;32023094;23710779 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31824473/
RECORD: Rec_0074704 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
E. faecium
10.0 μM
MIC
PaperInvestigation of the role of tryptophan residues in cationic antimicrobial peptides to determine the mechanism of antimicrobial action.
RECORD: Rec_0081154 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli AS1.349
9.37 μM
MIC
PMID31824473;32023094;23710779 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31824473/
RECORD: Rec_0090945 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterobacter cloacae CGMCC 1.58
100 μM
MIC
PMID31824473;32023094;23710779 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31824473/
1 2 3 ... 6 NEXT LAST
Showing 5 records on this page · Page 1 of 6