Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length107 amino acids

Chemical FormulaC521H817N139O155S8

DescriptionStandard

        MRTAFLIHRGLLSAVPLTLLSAILLVDLQAWTEPLQARTDEMPAQEQPPANDQDVVIYFSGDDSSSLQVPGSRKGLICHCSVLYCLFGEHLGGTCFIHSERSPICCY
    

Molecular Weight11764.42 Da

Isoelectric Point (pI)5.09

Net Charge (pH 7.0)-5.19

Net Charge (pH 7.4) -5.72

Charge Density (pH 7.0) -0.0485

GRAVY Index0.18

Hydrophobic Moment 0.56

Boman Index0.15

Instability Index62.26

Aliphatic Index 99.35

Aromaticity 0.0748

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4628.49

LogP -43.81

H-bond Donors 164.0

H-bond Acceptors 162.0

Rotatable Bonds 376.0

Heavy Atoms 823.0

Ring Count 20.0

Amide Bonds 113.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0414331 VERIFIED: NO

Provenance & Taxonomy

OrganismTheropithecus gelada [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence