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MYP_145909
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Basic Information
GBV-A10 [G6L]
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Standard
18 amino acids
C110H180N32O22S
Standard
Sequence
CWVRLLRYLLRRLKTPFT
Physicochemical Analysis
2334.87 Da
11.56
4.75
4.53
0.2638
0.08
0.96
-0.15
72.90
124.44
0.1667
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
899.33
-3.18
36.0
28.0
74.0
165.0
5.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0033790 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Hepatitis C virus (HCV) PsV
PMID23175359 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175359/
RECORD: Rec_0170778 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
5
PaperScreening and rational design of hepatitis C virus entry inhibitory peptides derived from GB virus A NS5A. J Virol. 2013 Feb;87(3):1649-1657. doi: 10.1128/JVI.02201-12. PMID: 23175359. PMID23175359 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175359/
RECORD: Rec_0194444 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperScreening and rational design of hepatitis C virus entry inhibitory peptides derived from GB virus A NS5A. J Virol. 2013 Feb;87(3):1649-1657. doi: 10.1128/JVI.02201-12. PMID: 23175359. PMID23175359 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175359/
RECORD: Rec_0246703 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
hepatitis C virus(Jc1-Luc HCVcc):inhibition of virus entry in Huh7
PaperScreening and rational design of hepatitis C virus entry inhibitory peptides derived from GB virus A NS5A. J Virol. 2013 Feb;87(3):1649-1657. doi: 10.1128/JVI.02201-12. PMID: 23175359. PMID23175359 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175359/
RECORD: Rec_0309208 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HCV Entry inhibition
Hepatitis C virus(Jc1-Luc HCVcc) | Huh7.5.1 cells
1.25 μM
IC50
Mammalian: 1.2 h; Yeast: >20 h; E. coli: >10 h
PaperScreening and rational design of hepatitis C virus entry inhibitory peptides derived from GB virus A NS5A. | Liu X, Huang Y, Cheng M, Pan L, Si Y, Li G, Niu Y, Zhao L, Zhao J, Li X, Chen Y, Yang W. | J Virol. 2013 Feb;87(3):1649-57. | DOI:10.1128/JVI.02201-12 | PMID:23175359 PMID23175359 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175359/
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