Peptide Database

Peptide NameS20

Function Ontology

Immunology ▸ Cytokine / receptor signaling modulation ▸ TLR inhibition

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC152H263N59O34S

DescriptionStandard

        TILEEYFMYRGLLGLRIRRRRRRRRR
    

Molecular Weight3493.15 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)8.40

Net Charge (pH 7.4) 8.21

Charge Density (pH 7.0) 0.3231

GRAVY Index-1.22

Hydrophobic Moment 0.47

Boman Index-0.73

Instability Index212.55

Aliphatic Index 90.00

Aromaticity 0.1154

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1607.01

LogP -13.04

H-bond Donors 65.0

H-bond Acceptors 44.0

Rotatable Bonds 123.0

Heavy Atoms 246.0

Ring Count 3.0

Amide Bonds 25.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0284885 VERIFIED: YES

Provenance & Taxonomy

OrganismOrthopoxvirus vaccinia [Virus]

FamilyP13/A52R-derived

Tax ID10245.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Anti-inflammatory TLR inhibitor

TargetCpG- or LPS-stimulated RAW264.7 macrophage assays