MYP_145837
Esculentin-1S (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Standard
46 amino acids
C212H364N58O58S4
Standard
GLFSKFAGKGIKNMIIKGIKGIGKEVGMDVIRTGIDVAGCKIKGEC
4781.77 Da
9.63
4.74
4.49
0.1030
0.25
0.70
0.15
-13.68
99.57
0.0435
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1875.63
-15.97
67.0
67.0
174.0
332.0
2.0
46.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0407468
VERIFIED: YES
Provenance & Taxonomy
Odorrana schmackeri [Animal]
Esculentin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
40-46
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Escherichia coli ATCC 25922
1.7 μM
MIC
RECORD: Rec_0414447
VERIFIED: YES
Provenance & Taxonomy
Odorrana schmackeri [Animal]
Esculentin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
40-46
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Staphylococcus aureus
3.0 μM
MIC
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