Peptide Database

Peptide NameSLAY-screened peptide P3251

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC103H146N24O32S3

DescriptionStandard

        KPDAMCSYQASVHDFSYCYL
    

Molecular Weight2328.60 Da

Isoelectric Point (pI)5.21

Net Charge (pH 7.0)-1.17

Net Charge (pH 7.4) -1.46

Charge Density (pH 7.0) -0.0587

GRAVY Index-0.21

Hydrophobic Moment 0.24

Boman Index0.08

Instability Index-1.81

Aliphatic Index 44.00

Aromaticity 0.2000

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 901.20

LogP -8.16

H-bond Donors 33.0

H-bond Acceptors 35.0

Rotatable Bonds 70.0

Heavy Atoms 162.0

Ring Count 6.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0069774 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/