Peptide Database

Peptide NameKawaguchipeptin peptide (Cyclic cyanobactin) [Cleaved into: Kawaguchipeptin A (Non-posttranslationnaly modified kawaguchipeptin B)]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC410H606N112O130S

DescriptionStandard

        MKNPTLLPKLTAPVERPAVTSSDLKQASSVDAAWLNGDNNWSTPFAGVNAAWLNGDNNWSTPFAGVNAAWLNGDNNWSTPFAADGAE
    

Molecular Weight9215.93 Da

Isoelectric Point (pI)4.31

Net Charge (pH 7.0)-4.49

Net Charge (pH 7.4) -4.72

Charge Density (pH 7.0) -0.0516

GRAVY Index-0.41

Hydrophobic Moment 0.55

Boman Index0.10

Instability Index23.30

Aliphatic Index 64.14

Aromaticity 0.1034

Extinction Coeff. Reduced 33000.00

Extinction Coeff. Oxidized 33000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3860.65

LogP -46.64

H-bond Donors 127.0

H-bond Acceptors 127.0

Rotatable Bonds 280.0

Heavy Atoms 653.0

Ring Count 22.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0421090 VERIFIED: YES

Provenance & Taxonomy

OrganismMicrocystis aeruginosa [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)