Peptide Database

Peptide NameDefensin-7

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC448H724N120O143S10

DescriptionStandard

        MKMLACLAAILLVVLQTQTDALPVGTEEDPVQEQTGAEDQDVTTHLTQTESPVLETTGPVKNVTCSCRARFCYRQERVEGPCNIFGMKFILCCY
    

Molecular Weight10399.91 Da

Isoelectric Point (pI)4.64

Net Charge (pH 7.0)-5.46

Net Charge (pH 7.4) -5.85

Charge Density (pH 7.0) -0.0581

GRAVY Index-0.00

Hydrophobic Moment 0.49

Boman Index0.06

Instability Index63.84

Aliphatic Index 83.94

Aromaticity 0.0532

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4218.87

LogP -43.85

H-bond Donors 149.0

H-bond Acceptors 149.0

Rotatable Bonds 341.0

Heavy Atoms 721.0

Ring Count 11.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0075434 VERIFIED: NO

Provenance & Taxonomy

OrganismTupaia chinensis [Animal]

FamilyDefensin

Tax ID246437

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal