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MYP_145737
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Basic Information
Sph12-38
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
27 amino acids
C132H228N48O31
Standard
Sequence
KAKAKAVSRSARAGLQFPVGRIHRHLK
Physicochemical Analysis
2983.53 Da
12.00
7.93
7.62
0.2937
-0.56
0.70
-0.26
62.00
83.33
0.0370
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1303.72
-13.68
48.0
41.0
103.0
211.0
4.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0139778 VERIFIED: YES
Provenance & Taxonomy
Scylla paramamosain [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas fluorescens
6 μM
MBC
PMID28600196 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28600196/
RECORD: Rec_0147893 VERIFIED: YES
Provenance & Taxonomy
Scylla paramamosain [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
1.5-3 μM
MIC
PMID28600196 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28600196/
RECORD: Rec_0150748 VERIFIED: YES
Provenance & Taxonomy
Scylla paramamosain [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas fluorescens
0.75-1.5 μM
MIC
PMID28600196 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28600196/
RECORD: Rec_0157565 VERIFIED: YES
Provenance & Taxonomy
Scylla paramamosain [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Vibrio harveyi
48 μM
MIC
PMID28600196 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28600196/
RECORD: Rec_0163874 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HeLa (Not active up to 100 μg/ml)
PaperPubMed PMID: 28600196 PMID28600196 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28600196/
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