Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length454 amino acids

Chemical FormulaC2251H3510N602O628S13

DescriptionStandard

        TNPGFVVRITQAGLDYAHEQGIAILEKELAQLKLPDISGDFRIQHVGKLHYDISSLDLRSFRLPYSRISLVPGVGLQVSISNAFAEVDGNWRVKLHFIRDHGSFDLEAEDVYIKIDLKLGSDAAGKPTIDTSGCTTHISRVWVHFSGKFGWLYNLFYGAVEPTFRRSLEREVCETVAWSVRRELQPYLQTLPVTARIDAMAGIDYSLVAPPAATAQSLDAGLKGEFFSLAHRSAVPFPPLALALPPDHDRMVYFGASSYFFNTAGFAYHAAGALVFEVTESMVVSPRDGGLCHCPHPLPAPLQLEKMYPDMAMKLRLSTPSAPFLSIGPGGLSLRPVVDIQAYAILPNSSLAPLFLLSLVSNVSAVVGVRSGRIVGSLEVGRYGAGAAQGVAGECFPLLLPPPSAPQVRMLQSIMNTVAFSALLPRLNDRLDQGFPLPLPDRIQLSNILVRFHQ
    

Molecular Weight49470.45 Da

Isoelectric Point (pI)6.65

Net Charge (pH 7.0)-1.47

Net Charge (pH 7.4) -2.47

Charge Density (pH 7.0) -0.0032

GRAVY Index0.15

Hydrophobic Moment 0.69

Boman Index0.15

Instability Index44.40

Aliphatic Index 100.33

Aromaticity 0.0925

Extinction Coeff. Reduced 42860.00

Extinction Coeff. Oxidized 43110.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0034711 VERIFIED: NO

Provenance & Taxonomy

OrganismCorythaixoides concolor [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria