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MYP_145695
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Basic Information
Temporin-LTc
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
17 amino acids
C99H149N21O22
Standard
Sequence
SLSRFLSFLKIVYPPAF
Physicochemical Analysis
1985.37 Da
9.99
1.46
1.25
0.0858
0.88
0.49
0.34
31.24
114.71
0.2353
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
680.18
-1.93
24.0
24.0
59.0
142.0
6.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0095182 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
Temporin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
100.0 μM
HC50
PaperH. Wang et al. / Peptides 30 (2009) 273-282. The novel antimicrobial peptides from skin of Chinese broad-folded frog, Hylarana latouchii (Anura:Ranidae) Evidence URLhttps://www.uniprot.org/uniprotkb/B9UYA2/entry
RECORD: Rec_0147296 VERIFIED: YES
Provenance & Taxonomy
Rana latouchii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
B. subtilis
50 μg/mL
MIC
RECORD: Rec_0158296 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 23.5%, E 0.0%, T 58.8%, C 17.6% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0201505 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
Temporin
156873
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Bacillus subtilis
50 μg/mL
MIC
PaperThe novel antimicrobial peptides from skin of Chinese broad-folded frog, Hylarana latouchii (Anura:Ranidae).
RECORD: Rec_0217868 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Rabbit erythrocytes
200 μg/mL
LD50
PMID19022312 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19022312/
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