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MYP_145695
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Basic Information
Temporin-LTc
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
17 amino acids
C99H149N21O22
Standard
Sequence
SLSRFLSFLKIVYPPAF
Physicochemical Analysis
1985.37 Da
9.99
1.46
1.25
0.0858
0.88
0.49
0.34
31.24
114.71
0.2353
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
680.18
-1.93
24.0
24.0
59.0
142.0
6.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0047839 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
Temporin
156873
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Staphylococcus aureus
50 μg/mL
MIC
PaperThe novel antimicrobial peptides from skin of Chinese broad-folded frog, Hylarana latouchii (Anura:Ranidae).
RECORD: Rec_0074534 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiviral
Pseudomonas fluorescens
100 μg/mL
MIC
PMID19022312 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19022312/
RECORD: Rec_0075802 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 2592
50 μg/mL
MIC
PMID19022312 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19022312/
RECORD: Rec_0084856 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0085034 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis ATCC 6633
50 μg/mL
MIC
PMID19022312 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19022312/
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