Peptide Database

Peptide NameF2,5,12W

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC100H160N38O16

DescriptionStandard

        RWGRWLRKIRRWRPK
    

Molecular Weight2150.59 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)7.76

Net Charge (pH 7.4) 7.55

Charge Density (pH 7.0) 0.5172

GRAVY Index-2.08

Hydrophobic Moment 0.99

Boman Index-0.85

Instability Index183.41

Aliphatic Index 52.00

Aromaticity 0.2000

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 932.74

LogP -4.58

H-bond Donors 38.0

H-bond Acceptors 24.0

Rotatable Bonds 70.0

Heavy Atoms 154.0

Ring Count 7.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0398598 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic peptide

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiofilm Antibacterial

TargetStaphylococcus epidermidis

Activity20, 40, 10 μM

MethodCrystal violet assay; Resazurin assay

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