Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC86H135N25O24S9

DescriptionStandard

        GCRFCCGCCPDMVGCGVCCKF
    

Molecular Weight2191.73 Da

Isoelectric Point (pI)7.70

Net Charge (pH 7.0)0.68

Net Charge (pH 7.4) 0.36

Charge Density (pH 7.0) 0.0324

GRAVY Index0.99

Hydrophobic Moment 0.33

Boman Index0.22

Instability Index11.06

Aliphatic Index 27.62

Aromaticity 0.0952

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 761.75

LogP -9.02

H-bond Donors 34.0

H-bond Acceptors 34.0

Rotatable Bonds 67.0

Heavy Atoms 144.0

Ring Count 3.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0293040 VERIFIED: YES

Provenance & Taxonomy

OrganismLithognathus mormyrus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)