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MYP_145686
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Basic Information
EB(H2R)-lytic
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
32 amino acids
C183H306N46O39
Standard
Sequence
YRWYGYTPQNVIGGGKLLLKLLKKLLKLLKKK
Physicochemical Analysis
3774.67 Da
10.42
8.75
8.53
0.2734
-0.27
0.84
-0.02
4.20
130.94
0.1250
9970.00
9970.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1409.58
-4.04
50.0
48.0
133.0
268.0
6.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0106416 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
LNCaP
4.8 μM
IC50
PaperSelective anticancer chimeric peptide comprising an EGF receptor-binding peptide and a cytotoxic peptide Evidence URLhttps://patents.google.com/patent/US8436137B2/en PatentUS8436137B2
RECORD: Rec_0199077 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
BT-20
1.9 μM
IC50
PaperSelective anticancer chimeric peptide comprising an EGF receptor-binding peptide and a cytotoxic peptide Evidence URLhttps://patents.google.com/patent/US8436137B2/en PatentUS8436137B2
RECORD: Rec_0210122 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
U-251
8.4 μM
IC50
PaperSelective anticancer chimeric peptide comprising an EGF receptor-binding peptide and a cytotoxic peptide Evidence URLhttps://patents.google.com/patent/US8436137B2/en PatentUS8436137B2
RECORD: Rec_0216639 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
H-322
3.2 μM
IC50
PaperSelective anticancer chimeric peptide comprising an EGF receptor-binding peptide and a cytotoxic peptide Evidence URLhttps://patents.google.com/patent/US8436137B2/en PatentUS8436137B2
RECORD: Rec_0218152 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
BxPC-3
6.6 μM
IC50
PaperSelective anticancer chimeric peptide comprising an EGF receptor-binding peptide and a cytotoxic peptide Evidence URLhttps://patents.google.com/patent/US8436137B2/en PatentUS8436137B2
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