MYP_145642
Gramicidin S [Orn2,7K], GS [Orn2,7K]
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Antimicrobial
▸
Antifungal
Reproductive biology
▸
Contraceptive activity
▸
Spermicidal
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Standard
10 amino acids
C62H98N12O11
Standard
VKLFPVKLFP
1187.52 Da
10.00
1.73
1.52
0.1732
1.06
0.20
0.39
44.04
136.00
0.2000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
359.68
1.92
11.0
13.0
35.0
85.0
4.0
9.0
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
RECORD: Rec_0113604
VERIFIED: YES
Provenance & Taxonomy
Bacillus brevis [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
The second and seventh residues of this cyclic peptide are Ornithines, an analog of lysine (one CH2 shorter). They are represented here with lysines. In addition, residue F is a D-amino acid. Even earlier reports are in Russian. Sergiev PG summarized some results on the peptide Science_direct. See also Biochem J. 1945;39(4):363-7. Pub-Med. Structure: Both X-ray and NMR have been used for stuctural studies (NMR+x)
Bio-Activity Profile
Antimicrobial
Antifungal
Spermicidal
15 Staphylococcus aureus
3.9-7.8 μg/mL
MIC
RECORD: Rec_0142099
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial
Antibacterial
Staphylococcus epidermidis NBRC 12933
6.25 μg/mL
MIC
RECORD: Rec_0178680
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial
Antibacterial
Staphylococcus aureus NBRC 12732
6.25 μg/mL
MIC
RECORD: Rec_0181052
VERIFIED: YES
Provenance & Taxonomy
Bacillus brevis [Bacterium]
Bacteriocin
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
The 'O' in sequence is Ornithine
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anti-Gram-positive
Anti-Gram-negative
Gram-negative (broad-spectrum)
RECORD: Rec_0192069
VERIFIED: YES
Provenance & Taxonomy
Bacillus brevis [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
The second and seventh residues of this cyclic peptide are Ornithines, an analog of lysine (one CH2 shorter). They are represented here with lysines. In addition, residue F is a D-amino acid. Even earlier reports are in Russian. Sergiev PG summarized some results on the peptide Science_direct. See also Biochem J. 1945;39(4):363-7. Pub-Med. Structure: Both X-ray and NMR have been used for stuctural studies (NMR+x)
Bio-Activity Profile
Antimicrobial
Antifungal
Spermicidal
15 Pseudomonas aeruginosa
31.2-62.5 μg/mL
MIC
Showing 5 records on this page · Page 2 of 4