Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC157H268N44O47S

DescriptionStandard

        MQEKRQQLVRVVSDTELEVLIGGKGPGLVKTF
    

Molecular Weight3556.14 Da

Isoelectric Point (pI)8.25

Net Charge (pH 7.0)0.51

Net Charge (pH 7.4) 0.28

Charge Density (pH 7.0) 0.0158

GRAVY Index-0.16

Hydrophobic Moment 0.58

Boman Index-0.02

Instability Index38.40

Aliphatic Index 106.25

Aromaticity 0.0312

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1497.65

LogP -13.50

H-bond Donors 51.0

H-bond Acceptors 49.0

Rotatable Bonds 125.0

Heavy Atoms 249.0

Ring Count 2.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0226015 VERIFIED: NO

Provenance & Taxonomy

OrganismDolosigranulum pigrum [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear lantibiotic precursor [Linear]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLantibiotic-family precursor annotation suggests post-translational lanthionine/methyllanthionine thioether crosslinks in the mature peptide

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria

MethodQualitative functional evidence