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MYP_145605
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Basic Information
Apidaecin IB
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Standard
18 amino acids
C95H150N32O23
Standard
Sequence
GNNRPVYIPQPRPPHPRL
Physicochemical Analysis
2108.41 Da
11.71
2.85
2.59
0.1581
-1.44
0.30
-0.30
53.16
59.44
0.0556
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
869.16
-8.22
27.0
27.0
57.0
150.0
8.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0383904 VERIFIED: NO
Provenance & Taxonomy
Apis mellifera [Animal]
7460
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
RECORD: Rec_0397590 VERIFIED: YES
Provenance & Taxonomy
Apis mellifera [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas syringae pv
PMID2676519;2298215 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2676519/
RECORD: Rec_0401122 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperCasteels P., Ampe C., Jacobs F., Vaeck M., Tempst P.;. "Apidaecins: antibacterial peptides from honeybees."; EMBO J. 8:2387-2391. Evidence URLhttps://www.uniprot.org/uniprotkb/AP14_APIME/entry
RECORD: Rec_0415108 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Evidence URLhttps://patents.google.com/patent/US5466671A/en PatentUS 5466671 A
RECORD: Rec_0416661 VERIFIED: YES
Provenance & Taxonomy
Apis florea [Animal]
Apidaecin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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