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MYP_145602
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
3 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
RXR
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0201244 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Peptidomimetic AMP
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Tbt residue and ethylphenyl peptidomimetic group
Bio-Activity Profile
Antibacterial
Linezolid-nonsusceptible Staphylococcus aureus (LNSSA)
4 μg/mL
MBC
PaperIn vitro activities of LTX-109, a synthetic antimicrobial peptide, against methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, daptomycin-nonsusceptible, and linezolid-nonsusceptible Staphylococcus aureus.Antimicrob Agents Chemother. 2012 PMID22585222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22585222/
RECORD: Rec_0244929 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 2
Bio-Activity Profile
Hemolytic
human red blood cells
10 % hemolysis at >256 μg/mL
Hemolysis
PMID26489599;24302996 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26489599/
RECORD: Rec_0252790 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Peptidomimetic AMP
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Tbt residue and ethylphenyl peptidomimetic group
Bio-Activity Profile
Antibacterial
Daptomycin-nonsusceptible Staphylococcus aureus(DNSSA)
2-4 μg/mL
MIC
PaperIn vitro activities of LTX-109, a synthetic antimicrobial peptide, against methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, daptomycin-nonsusceptible, and linezolid-nonsusceptible Staphylococcus aureus.Antimicrob Agents Chemother. 2012 PMID22585222 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22585222/
RECORD: Rec_0263012 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 2
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli KCTC 1682
32 μg/mL
MIC
PMID26489599;24302996 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26489599/
RECORD: Rec_0265491 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 2
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis KCTC 1917
8 μg/mL
MIC
PMID26489599;24302996 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26489599/
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