Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length52 amino acids

Chemical FormulaC263H427N87O77S6

DescriptionStandard

        RSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKWDESLLNRTKP
    

Molecular Weight6232.13 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)6.71

Net Charge (pH 7.4) 6.40

Charge Density (pH 7.0) 0.1290

GRAVY Index-1.07

Hydrophobic Moment 0.58

Boman Index-0.43

Instability Index52.96

Aliphatic Index 48.85

Aromaticity 0.0962

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2741.95

LogP -30.83

H-bond Donors 107.0

H-bond Acceptors 90.0

Rotatable Bonds 210.0

Heavy Atoms 433.0

Ring Count 8.0

Amide Bonds 54.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0125429 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo pygmaeus [Animal]

FamilyDefensin

Tax ID9600

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0315495 VERIFIED: NO