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MYP_145561
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Basic Information
Defensin VpDef
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
49 amino acids
C218H335N73O75S8
Standard
Sequence
GFGCPEDEYECHNHCKNSVGCRGGYCDAGTLRQRCTCYGCNQKGRSIQE
Physicochemical Analysis
5434.96 Da
6.87
-0.13
-0.57
-0.0027
-1.00
0.47
-0.24
62.04
23.88
0.0816
4470.00
4970.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2432.28
-34.66
92.0
85.0
180.0
374.0
7.0
54.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0374738 VERIFIED: YES
Provenance & Taxonomy
Venerupis philippinarum [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
E. aerogenes
12.5-25 μM
MIC
PaperA defensin from clam venerupis philippinarum: molecular characterization, localization, antibacterial activity, and mechanism of action
RECORD: Rec_0377267 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0385538 VERIFIED: YES
Provenance & Taxonomy
Venerupis philippinarum [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
25-50 μM
MIC
PaperA defensin from clam venerupis philippinarum: molecular characterization, localization, antibacterial activity, and mechanism of action
RECORD: Rec_0398990 VERIFIED: YES
Provenance & Taxonomy
Ruditapes philippinarum [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Proteus mirabilis
50-100 μM
MIC
PMID25697801 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25697801/
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