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MYP_145538
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Basic Information
Polymyxin CAMP113
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
10 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XTXCXFXRXC
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0094560 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
D-residue-containing modified peptide [Mixed]
unspecified non-canonical residue at 1,3,5,7,9
Bio-Activity Profile
Antimicrobial Antibacterial
Human hepatocellular carcinoma HepG2
80-90 % Killing
Killing
PMID30215733 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30215733/
RECORD: Rec_0096262 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
D-residue-containing modified peptide [Mixed]
unspecified non-canonical residue at 1,3,5,7,9
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
4 μg/mL
MIC
PMID30215733 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30215733/
RECORD: Rec_0107455 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
D-residue-containing modified peptide [Mixed]
unspecified non-canonical residue at 1,3,5,7,9
Bio-Activity Profile
Antimicrobial Antibacterial
Human hepatocellular carcinoma HepG2
40-50 % Killing
Killing
PMID30215733 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30215733/
RECORD: Rec_0306631 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
D-residue-containing modified peptide [Mixed]
unspecified non-canonical residue at 1,3,5,7,9
Bio-Activity Profile
Antimicrobial Antibacterial
Human hepatocellular carcinoma HepG2
90-100 % Killing
Killing
PMID30215733 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30215733/
RECORD: Rec_0314396 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
C12
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID30215733 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30215733/
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