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MYP_145537
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Basic Information
Rabbit neutrophil peptide 4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
33 amino acids
C143H238N54O44S6
Standard
Sequence
VSCTCRRFSCGFGERASGSCTVNGVRHTLCCRR
Physicochemical Analysis
3610.14 Da
9.30
4.76
4.41
0.1444
-0.16
0.53
-0.21
90.52
41.21
0.0606
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1616.60
-25.07
68.0
56.0
118.0
247.0
3.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0255055 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperSelsted M. E., Brown D. M, DeLange R. J., Harwig S. S., Lehrer R. I.. Primary structures of six antimicrobial peptides of rabbit peritoneal neutrophils. J. Biol. Chem., 260, 4579-4584, 1985.
RECORD: Rec_0268881 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Three disulfide bridges
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus strains 566, 502A, J.F. (reduction 0.1-0.2 logs), Staphylococcus epidermidis UCLA-622 (reduction 0.2 logs), S. pneumoniae Type III (reduction 4.3 log), S. agalactiae Type I-A
PaperPrimary structures of six antimicrobial peptides of rabbit peritoneal neutrophils
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