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MYP_145537
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Basic Information
Rabbit neutrophil peptide 4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
33 amino acids
C143H238N54O44S6
Standard
Sequence
VSCTCRRFSCGFGERASGSCTVNGVRHTLCCRR
Physicochemical Analysis
3610.14 Da
9.30
4.76
4.41
0.1444
-0.16
0.53
-0.21
90.52
41.21
0.0606
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1616.60
-25.07
68.0
56.0
118.0
247.0
3.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0022363 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0035850 VERIFIED: NO
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Defensin
9986
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperNeutrophil antibiotic peptide NP-4 Evidence URLhttps://www.uniprot.org/uniprotkb/P07467/entry
RECORD: Rec_0050636 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0135757 VERIFIED: NO
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
9986
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-31; 5-20; 10-30
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0170038 VERIFIED: YES
Provenance & Taxonomy
Mammalia [Animal]
40674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID3988726 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3988726/
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