Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 1.6

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Potassium channel modulation ▸ Potassium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC178H278N52O52S7

DescriptionStandard

        QFTNVSCSASSQCWPVCKKLFGTYRGKCMNSKCRCYS
    

Molecular Weight4202.88 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)5.69

Net Charge (pH 7.4) 5.40

Charge Density (pH 7.0) 0.1539

GRAVY Index-0.38

Hydrophobic Moment 0.46

Boman Index-0.12

Instability Index27.48

Aliphatic Index 28.92

Aromaticity 0.1351

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1720.46

LogP -22.52

H-bond Donors 68.0

H-bond Acceptors 65.0

Rotatable Bonds 137.0

Heavy Atoms 289.0

Ring Count 7.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0176162 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilyPotassium channel inhibitor family

Tax ID34649; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

Disulfide7-28; 13-33; 17-35

Bio-Activity Profile

Function

Toxin Venom Potassium channel inhibitor family Ion channel inhibitor Pathogenesis-associated Host defense

RECORD: Rec_0341019 VERIFIED: YES