Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length101 amino acids

Chemical FormulaC455H744N142O150S7

DescriptionStandard

        MRTLALLAALLLVALQAHAEPLQAQGGQLQETAEQAPAEEQPGVQDQDVAISFAEDESSGLRAAGSTRRLSCYCRRGSCPRPERTYGTCTSGGLRYTLCCR
    

Molecular Weight10828.09 Da

Isoelectric Point (pI)5.76

Net Charge (pH 7.0)-1.45

Net Charge (pH 7.4) -1.82

Charge Density (pH 7.0) -0.0143

GRAVY Index-0.32

Hydrophobic Moment 0.71

Boman Index-0.07

Instability Index72.07

Aliphatic Index 76.53

Aromaticity 0.0396

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4719.07

LogP -59.65

H-bond Donors 171.0

H-bond Acceptors 157.0

Rotatable Bonds 357.0

Heavy Atoms 754.0

Ring Count 10.0

Amide Bonds 109.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0108044 VERIFIED: NO

Provenance & Taxonomy

OrganismOtolemur garnettii [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence