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MYP_145500
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Basic Information
Bac7 (1-35)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
35 amino acids
C196H322N68O36
Standard
Sequence
RRIRPRPPRLPRPRPRPLPFPRPGPRPIPRPLPFP
Physicochemical Analysis
4207.09 Da
12.00
10.76
10.56
0.3074
-1.41
0.80
-0.49
96.07
55.71
0.0571
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1592.98
-10.78
53.0
47.0
111.0
300.0
18.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000873 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
MKP103 wza mutant (
0.5 μg/mL
MIC
PMID35254120 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35254120/
RECORD: Rec_0005540 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
PrAMP
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S-enterica Ser. Typhimurium ATCC 14028
>64 μM
MIC
PaperAntimicrobial activity of Bac7 fragments against drug-resistant clinical isolates
RECORD: Rec_0021371 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
ATCC 43816
0.25 μg/mL
MIC
PMID35254120 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35254120/
RECORD: Rec_0054007 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
S. marcescens ATCC 8100
1 μM
MIC
PaperIn vitro effect on Cryptosporidium parvum of short-term exposure to cathelicidin peptides.
RECORD: Rec_0057076 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID33036159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33036159/
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