Peptide Database

Peptide NamePAFopt

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length55 amino acids

Chemical FormulaC267H433N77O86S6

DescriptionStandard

        AKYTGKCKTKKNKCKYKNDAGKDTFIKCPKFDNKKCTKDNNKCTVDTYNNAVDCD
    

Molecular Weight6290.15 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)7.73

Net Charge (pH 7.4) 7.42

Charge Density (pH 7.0) 0.1405

GRAVY Index-1.44

Hydrophobic Moment 0.42

Boman Index-0.42

Instability Index27.43

Aliphatic Index 23.09

Aromaticity 0.0909

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2761.03

LogP -34.66

H-bond Donors 99.0

H-bond Acceptors 100.0

Rotatable Bonds 222.0

Heavy Atoms 436.0

Ring Count 6.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0130737 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida albicans CBS 5982

Activity1.3 μM

MethodMIC

RECORD: Rec_0348729 VERIFIED: YES