Peptide Database

Peptide NameChimeric CNP-E

Function Ontology

Natriuretic

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC223H384N70O61S3

DescriptionStandard

        CFGLKLDRIGSMSGLGCVQQRKESKKPPAKLQPRESKKPPAKLQPR
    

Molecular Weight5118.06 Da

Isoelectric Point (pI)10.46

Net Charge (pH 7.0)8.74

Net Charge (pH 7.4) 8.49

Charge Density (pH 7.0) 0.1900

GRAVY Index-1.02

Hydrophobic Moment 0.50

Boman Index-0.32

Instability Index53.97

Aliphatic Index 61.52

Aromaticity 0.0217

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2141.02

LogP -23.07

H-bond Donors 74.0

H-bond Acceptors 73.0

Rotatable Bonds 177.0

Heavy Atoms 357.0

Ring Count 7.0

Amide Bonds 49.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0084624 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyNatriuretic peptide

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide1-17

Bio-Activity Profile

Function

Natriuretic

MethodCompetitive Radioimmunoassay

Half-LifeRat plasma (Intravenous), in vivo; 1104 s