Peptide Database

Peptide NameBeta-defensin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC328H535N95O89S7

DescriptionStandard

        MRVLHLLLLALGLLFSQLGPGAGQLTALGQWSDSYICARKGGTCNLSPCPLYNRVEGTCYRGKAKCCIR
    

Molecular Weight7457.79 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)5.53

Net Charge (pH 7.4) 5.16

Charge Density (pH 7.0) 0.0801

GRAVY Index0.22

Hydrophobic Moment 0.50

Boman Index0.11

Instability Index14.37

Aliphatic Index 100.43

Aromaticity 0.0725

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2940.13

LogP -28.52

H-bond Donors 110.0

H-bond Acceptors 103.0

Rotatable Bonds 244.0

Heavy Atoms 519.0

Ring Count 10.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0046111 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence