Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length517 amino acids

Chemical FormulaC2638H4074N664O749S22

DescriptionStandard

        MCTKMAQVQVQVLWGCFILWNLYISSAQAIYPGIKARATRRALDYAVQAGMEMIEQMAKERKLPDLKGSESLEFLKIDYVNYNFTNIKITAFSFPNTSLSFVPGVGIRALTNHGTTNISTDWDVKSPLFQDTGAADLFLSGVYFTGIVVLSRNDFGHPILKLQDCYAQVSHADVSFSGELSVLYNSFAEPMEKPILKKLNEMLCPIITGEVEALNANLSKLEVLRKMDNYTLLDYSLVSPPEITENYFDLNLKGVFYPLKSLQYPPFPSVPFVLPERSDSMLYIGISKYFFKSASYAYFTAGAFSFTLTTKEISNHLLHNSQALGNMLSRIAELYILSQPFMVQVMATEPPVIRLLPGNFTLDIPASIMILTQPKNSTAETIVSMDFVASTNVALAILGQRLIYWETNRGEKLSPQFYQVFKGLISPLNSIGMVPRAYETSETHENLPEVHKSALTLQTGFPGGTSSKKPSCPNAGDMRCWFVPWVGKIAWRRTWQPTPVFLPGESHGQRSLAGYNP
    

Molecular Weight57780.00 Da

Isoelectric Point (pI)7.08

Net Charge (pH 7.0)0.18

Net Charge (pH 7.4) -0.65

Charge Density (pH 7.0) 0.0004

GRAVY Index-0.00

Hydrophobic Moment 0.76

Boman Index0.13

Instability Index38.42

Aliphatic Index 90.35

Aromaticity 0.1141

Extinction Coeff. Reduced 76780.00

Extinction Coeff. Oxidized 77155.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0343293 VERIFIED: NO

Provenance & Taxonomy

OrganismMuntiacus reevesi [Animal]

FamilyBPI

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence